Everyone's "poo-pooing" the article because the title doesn't mention mice, but, FWIW, stories of gut biota affecting humans behavior have been documented for a while.
Memory gain is noteworthy, which is the article's "wow" factor, but everyone's just knee-jerk smirking so ... here's a few random articles to gross you out about the wild world of trading microbiota and, for better or worse, changing your personality:
* "My butt made me crave candy."[1]
* "Gee, I'm not bipolar anymore thanks to my husband's butt juice infusion."[2]
I would recommend the site https://gutbrainaxistherapeutics.com for learning more about Microbiota Transplant Therapy (MTT) and its opportunities, especially for Autism and Pitt-Hopkins Syndrome.
1shooner 19 minutes ago [-]
This seems to be a recent anti-science meme to dismiss studies that use mouse models. I'm sure there is an interesting line of discussion about the strengths and limits of those models, but that's probably a complex, nuanced thread to pull, not something you blow off with a hand-waving internet comment.
inanutshellus 10 minutes ago [-]
To some degree the other posts are just pointing out the misleading "assumed protagonist" of the title (which doesn't mention mice) but I was surprised to see that the majority of posts boiled down to "eek! mice!"
maxall4 51 minutes ago [-]
I smell bad data. This sounds too good to be true and most studies of this kind have turned out to be false a few years down the line.
... in mice. So if any of this held in humans, I think you'd see reversal of old-age memory problems in people treated with antibiotics that kill Parabacteroides goldsteinii.
As far as I know, no such effect has been observed.
And this article claims inflamation from that strain, the NIH claims otherwise: "Parabacteroides goldsteinii
is a next-generation probiotic gut bacterium with significant anti-inflammatory and metabolic benefits, often reduced in obese or diseased states. "
vidarh 49 minutes ago [-]
It's possible the specifics are different but that the overall idea still could work for humans. It seems worth at least exploring.
steve1977 1 hours ago [-]
[flagged]
j45 54 minutes ago [-]
in mice is clearly in the subhead.
The connection between gut-brain has been studied in humans, as well as teh effect of diet and gut bacteria on brain functions.
vidarh 51 minutes ago [-]
And in this case it sounds like the pathway to determining if this has an effect in humans as well might be relatively short given there is a pool of patients receiving vagus nerve stimulation for other things that might provide data.
Rendered at 18:43:56 GMT+0000 (Coordinated Universal Time) with Vercel.
Memory gain is noteworthy, which is the article's "wow" factor, but everyone's just knee-jerk smirking so ... here's a few random articles to gross you out about the wild world of trading microbiota and, for better or worse, changing your personality:
Crazy, right?Edit: one of many examples: https://www.science.org/content/article/journal-retracts-inf...
As far as I know, no such effect has been observed.
And this article claims inflamation from that strain, the NIH claims otherwise: "Parabacteroides goldsteinii is a next-generation probiotic gut bacterium with significant anti-inflammatory and metabolic benefits, often reduced in obese or diseased states. "
The connection between gut-brain has been studied in humans, as well as teh effect of diet and gut bacteria on brain functions.